The past year has shown that some old tricks no longer work and some new ones have been developed. Over the last year the Panda,Penguin and EMD updates by Google have made domainers and developers have to rethink their strategy.
Verisign cannot raise .com prices in their latest contract.
Frank Schilling opened up his InternetTraffic and DomainNameSales to just about every domainer.
Afternic and Sedo have made partnerships with just about every registrar out there.
Looking forward there will be a lot of new tlds that vie for the attention of the public and to domainers, especially new domainers who come into domains with the new tlds thinking they have found the next gold rush.
Portfolio focus will be more important than ever, there is not a need to own so so domains when future end users will have new options. Focus on quality whatever extension you like. Obviously the liquidity is in .com and the most popular ccTLDs.
Whatever you do make sure you read and have a budget. Stick to the budget and focus on your sell through rate. If you are not selling any domains, stop buying. Think of creative ways to sell and develop a name or two.
Have a great New Year.